Raghavendra Rao

Associate Professor, Department of Pediatrics, Division of Neonatology, University of Minnesota (USA)

Associate Professor, Department of Pediatrics, Division of Neonatology, University of Minnesota (USA)

Brain energy metabolism and injury; neuroprotection; iron deficiency and its effects on the brain; hypoglycemia and hyperglycemia.

1. Rao R, Tkac I, Townsend, EL, Gruetter R, Georgieff MK. Perinatal iron deficiency alters the neurochemical profile of the developing rat hippocampus. J Nutr 133:3215-3221, 2003. PMID: 14519813. 2. Ennis K, Tran PV, Seaquist ER, Rao R. Postnatal age influences hypoglycemia-induced neuronal injury in the rat brain. Brain Res 1224:119-26, 2008. PMID: 18582442. 3. Rao R, Ennis K, Long JD, Ugurbil K, Gruetter R, Tkac I. Neurochemical changes in the developing rat hippocampus during prolonged hypoglycemia. J Neurochem 114: 728-738, 2010. PMID: 20477939. 4. Ennis K, Dotterman H, Stein A, Rao R. Hyperglycemia accentuates and ketonemia attenuates hypoglycemia-induced neuronal injury in the developing rat brain. Pediatr Res 77: 84-90, 2015. PMID: 25279990. 5. Rao R, Ennis K, Mitchell EP, Tran PV, Gewirtz JC. Recurrent moderate hypoglycemia suppresses brain-derived neurotrophic factor expression in the prefrontal cortex and impairs sensorimotor gating in the posthypoglycemic period in young rats. Dev Neurosci 38: 78-82, 2016. (DOI: 10.1159/000442878). 6. Raman L, Tkac I, Ennis K, Gruetter R, Georgieff M.K., Rao R. In vivo effect of chronic hypoxia on the neurochemical profile of the developing rat hippocampus. Brain Res. Dev Brain Res 156:202-209, 2005. PMID: 16099307. 7. Rao R. Tkac I, Townsend E, Ennis K, Gruetter R, Georgieff M. Perinatal iron deficiency predisposes the developing rat hippocampus to greater injury from mild to moderate hypoxia-ischemia. J Cereb Blood Flow Metab 27: 729-740, 2007. PMID: 16868555. 8. Maliszewski-Hall AM, Alexander M, Ivan Tkáč I, Öz G, Rao R. Differential effects of intrauterine growth restriction on the regional neurochemical profile of the developing rat brain. Neurochem Res (2015 May 14. [Epub ahead of print]) PMID: 25972040. 9. Ennis K, Deelchand D, Tkac I, Henry P-G, Rao R. Determination of oxidative glucose metabolism in the developing rat brain using localized direct-detected in vivo 13C NMR spectroscopy. Neurochem Res 36: 1962-1968, 2011. PMID: 21660589. 10. Rao R, Ennis K, Oz G, Lubach G, Georgieff MK, Coe C. Metabolomic analysis of cerebrospinal fluid indicates iron deficiency compromises cerebral energy metabolism in the infant monkey. Neurochem Res 38: 573-80, 2013. PMID: 23269483. Link to all peer-reviewed publications: http://www.ncbi.nlm.nih.gov/sites/myncbi/raghavendra.rao.1/bibliography/43456038/public/?sort=date&direction=descending

1. NIH/NINDS 1U01 NS077953 “Preterm Epo Neuroprotection Trial (PENUT Trial) CCC”. PI: Juul, SE, University of Washington; 4/1/2013 to 3/31/2018. Role: Site-Principal Investigator; 5% effort with salary. 2. NIH/NHLBI 2P01HL046925-16A1 “Neonatal Anemia and Thrombocytopenia: Pathophysiology and Treatment”. PI: Georgieff MK/Widness J (Prime PI); 4/1/2012 to 3/31/2017, $187,360. Role: Co-Investigator; 10% effort with salary.